| 摘要 |
The invention relates to a method for preparing imrecoxib. In the method, with methylsulfonyl acetophenone as a raw material, the imrecoxib (structural formula I as shown in the specification) is prepared by synthesizing dihydrofuranone (structural formula II as shown in the specification) and then converting the dihydrofuranone (II) into pyrrolidone. The preparation method provided by the invention has the advantages of short synthetic route, low cost, simplicity in operation, easiness in separation and purification and suitability for large-scale production. |
