Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/HER3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of ErbB3/HER3.
申请公布号
US2013330772(A1)
申请公布日期
2013.12.12
申请号
US201313919582
申请日期
2013.06.17
申请人
AVEO PHARMACEUTICALS, INC.
发明人
VINCENT SYLVIE;WINSTON, JR. WILLIAM M.;WANG FANG;WEILER SOLLY;MEETZE KRISTAN;BREAULT LYNE;BOTTEGA STEVE;CHEN TING;DEPRIMA MICHAEL;FLEET CHRISTINA;TYLER STEVEN;WOO JIN-KYEUNG;GYURIS JENO
