发明名称 |
Human fusion proteins comprising interferons and targeted modified ubiquitin proteins |
摘要 |
The present invention relates to fusion proteins in which a pharmaceutically active component is fused to an antibody mimetic. The invention specifically concerns fusion proteins comprising interferons or biologically active muteins thereof and modified hetero-dimeric ubiquitin proteins as specific targeting domain. The invention further relates to these fusion proteins for use in medicine, in particular for use in the treatment of cancer or infectious diseases. The invention is further directed to pharmaceutical compositions comprising a pharmaceutically acceptable carrier in combination with such fusion proteins, and in combination with cancer therapeutic agents. Moreover, the invention relates to a method for the generation of said fusion proteins. |
申请公布号 |
AU2012268973(A1) |
申请公布日期 |
2013.12.12 |
申请号 |
AU20120268973 |
申请日期 |
2012.06.15 |
申请人 |
SCIL PROTEINS GMBH |
发明人 |
NERKAMP, JORG;HANSSGEN, ILKA;LANGE, CHRISTIAN;GLOSER, MANJA;STEUERNAGEL, ARND;KUNTZSCH, ANTJE |
分类号 |
C07K14/00;C12N15/10 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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