发明名称 CD3-binding molecules capable of binding to human and non-human CD3
摘要 The present invention relates to CD3 -binding molecules capable of binding to human and non-human CD3, and in particular to such molecules that are cross-reactive with CD3 of a non-human mammal (e.g., a cynomolgus monkey). The invention also pertains to uses of such antibodies and antigen-binding fragments in the treatment of cancer, autoimmune and/or inflammatory diseases and other conditions.
申请公布号 AU2012259161(A1) 申请公布日期 2013.12.12
申请号 AU20120259161 申请日期 2012.05.16
申请人 MACROGENICS, INC. 发明人 HUANG, LING;JOHNSON, LESLIE S.
分类号 A61K39/395 主分类号 A61K39/395
代理机构 代理人
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