发明名称 |
Extended release composition containing tramadol |
摘要 |
An oral tramadol pharmaceutical composition for once daily administration, containing an effective amount of tramadol or a pharmaceutically-acceptable salt thereof, providing in vivo, a time of tramadol peak plasma concentration (Tmax) greater than 10 hours and a peak tramadol plasma concentration (Cmax) which is less than three times a plasma concentration obtained 24 hours after administration (C24h) of a single dose of the composition. |
申请公布号 |
US2013330404(A1) |
申请公布日期 |
2013.12.12 |
申请号 |
US201213506390 |
申请日期 |
2012.04.17 |
申请人 |
DEBOECK ARTHUR M.;VANDERBIST FRANCIS;SERENO ANTONIO;GALEPHAR PHARMACEUTICAL RESEARCH, INC. |
发明人 |
DEBOECK ARTHUR M.;VANDERBIST FRANCIS;SERENO ANTONIO |
分类号 |
A61K31/135;A61K9/22;A61K9/50;A61K31/137 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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