发明名称 CRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR
摘要 Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
申请公布号 CA2875986(A1) 申请公布日期 2013.12.12
申请号 CA20132875986 申请日期 2013.06.03
申请人 PHARMACYCLICS, INC. 发明人 PURRO, NORBERT;SMYTH, MARK;GOLDMAN, ERICK;WIRTH, DAVID D.
分类号 A61K47/38;A61K9/48;A61K47/30;A61P29/00;A61P35/00 主分类号 A61K47/38
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