发明名称 |
PROCESS FOR MAKING EVEROLIMUS |
摘要 |
An improved process for making, stabilizing and monitoring the compound of general formula (3) in which R1,R2,R3 are independently a straight or branched alkyl group of 1 to 10 carbon atoms and/or a phenyl group, is provided. The compounds of formula (3) are important intermediates in making the pharmaceutically active compound everolimus. |
申请公布号 |
EP2670756(A1) |
申请公布日期 |
2013.12.11 |
申请号 |
EP20110707171 |
申请日期 |
2011.03.08 |
申请人 |
SYNTHON BV |
发明人 |
LUTEN, Jordy;KELTJENS, Rolf;BENES , Michal;JANOUSEK, Vladimir;PÍS, Jaroslav |
分类号 |
C07D498/18;A61K31/435;C07F7/18 |
主分类号 |
C07D498/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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