发明名称 |
Vacuna contra la tuberculosis |
摘要 |
The present invention relates to an isolated microorganism belonging to the Mycobacterium genus, characterised in that it comprises the inactivation of the Rv0757 gene that confers a PhoP- phenotype and the inactivation of a second gene that prevents DIM production (DIM- phenotype). Additionally, the present invention comprises the use of said microorganism for the preparation of a vaccine for the immunisation or prevention of tuberculosis. |
申请公布号 |
ES2433518(T3) |
申请公布日期 |
2013.12.11 |
申请号 |
ES20070730491T |
申请日期 |
2007.03.14 |
申请人 |
UNIVERSIDAD DE ZARAGOZA |
发明人 |
MARTIN MONTANES, CARLOS;GICQUEL, BRIGITTE;PEREZ HERRAN, ESTHER;GONZALO ASENSIO, JESUS;ARBUES ARRIBAS, AINHOA |
分类号 |
C12N1/21;A61K39/04;C07K14/35;C12N1/36;C12R1/32 |
主分类号 |
C12N1/21 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|