发明名称 2-aminooxazolines as TAAR1 ligands
摘要 The invention relates to compounds of formula I wherein X, Y, R1, R2, and n are as defined herein or to a pharmaceutically suitable acid addition salt thereof. The invention also relates to pharmaceutical compositions containing such compounds and methods for the treatment of diseases related to the biological function of the trace amine associated receptors, which diseases include depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, substance abuse and metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
申请公布号 US8604061(B2) 申请公布日期 2013.12.10
申请号 US201213426736 申请日期 2012.03.22
申请人 GALLEY GUIDO;GROEBKE ZBINDEN KATRIN;NORCROSS ROGER;STALDER HENRI;HOFFMANN-LA ROCHE INC. 发明人 GALLEY GUIDO;GROEBKE ZBINDEN KATRIN;NORCROSS ROGER;STALDER HENRI
分类号 A01N43/40;A61K31/44;C07D413/00 主分类号 A01N43/40
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