摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to substituted quinoxaline-type bridge piperidine compounds of formula,or pharmaceutically acceptable derivatives thereof, where: a equals 0; b is an integer selected from 0 or 1; each Ris independently selected from -H; Ris -(C-C)bicycloalkyl, each substituted with 1 or 2 independently selected Rgroups; each Rindependently selected from -(C-C)alkyl. The invention also relates to a pharmaceutical composition, capable of modulating ORL-1 receptor function, based on said compound.EFFECT: obtaining novel compounds which can be used in medicine to treat pain, memory disorder, obesity, constipation, depression, dementia, Parkinsonism, anxiety, cough, diarrhoea, high blood pressure, epilepsy, anorexia, urinary incontinence or drug dependence.27 cl, 2 tbl, 19 ex |