发明名称 Immunoassay for detection of neurotoxic amino acid associated with neurological disorders
摘要 An immunoassay for screening a sample to detect the presence of beta-N-methylamino-L-alanine (BMAA) is disclosed. Antibodies specific for BMAA are disclosed. Antibodies that bind to BMAA on immunoblots are disclosed. Immunoassays and kits to detect the presence of BMAA in a sample by contacting the sample with an antibody that binds to BMAA, and detecting the antibody bound to the sample, are disclosed. Immunoassays and kits for screening for the presence of BMAA in a subject by analyzing a tissue sample obtained from the subject to detect the present of BMAA in the tissue sample, where the presence of BMAA in the tissue sample indicates exposure of the subject to an environmental source of BMAA, are disclosed. Immunoassays and kits for detecting an environmental source of BMAA, by screening an environmental sample to detect the presence of BMAA in the sample, wherein the presence of a detectable amount of BMAA in the sample indicates the sample is an environmental source of BMAA, are disclosed.
申请公布号 US8603753(B2) 申请公布日期 2013.12.10
申请号 US200913056877 申请日期 2009.07.02
申请人 COX PAUL ALAN;METCALF JAMES S.;CODD GEOFFREY A.;THE INSTITUTE FOR ETHNOMEDICINE;THE UNIVERSITY OF DUNDEE 发明人 COX PAUL ALAN;METCALF JAMES S.;CODD GEOFFREY A.
分类号 G01N33/53 主分类号 G01N33/53
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