| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions refers to a complex of insulin and polysaccharide, containing functional carboxyl groups, wherein the above polysaccharide is specified in polysaccharides, particularly dextran functionalised by at least one phenylalanyl derivative referred to as Phe with the above phenylalanyl derivative is specified in a group consisting of phenylalanyl or cationic alkaline salts thereof, phenylalaninol, phenylalaninamide, ethylbenzylamine, or among phenylalanine esters, and the above insulin is either human insulin, or insulin analogue. The invention also refers to a pharmaceutical composition containing at least one complex according to the invention, particularly in the form of an injection solution, as well as to the methods for preparing the pharmaceutical composition.EFFECT: group of inventions enables the post-administration rapid insulin haemorrhage.23 cl, 15 ex, 5 dwg |
