METHOD FOR PREPARING CEPHALOSPORIN MICROCAPSULES IN INTERFERON

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to a method for preparing interferon-coated cephalosporin microcapsules. The declared method is characterized by mixing 1% aqueous solution of human leukocyte ?- or ?-interferon, cephalosporin powder and preparation E472c as a surfactant. The prepared mixture is stirred until the reaction components are fully dissolved, and after a transparent solution is generated, methanol 1 ml as a first non-solvent and then isopropyl alcohol 5 ml as a second non-solvent are slowly added drop-by-drop, then filtered, washed in acetone and dried.EFFECT: invention provides preparing the high-yield cephalosporin microcapsules and ensuring the loss reduction.8 ex