发明名称 |
Anti-TNF antibodies, compositions, methods and uses |
摘要 |
The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS:1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods. |
申请公布号 |
US8603778(B2) |
申请公布日期 |
2013.12.10 |
申请号 |
US201213547557 |
申请日期 |
2012.07.12 |
申请人 |
HEAVNER GEORGE;KNIGHT DAVID M.;GILES-KOMAR JILL;SCALLON BERNARD;SHEALY DAVID;JANSSEN BIOTECH, INC. |
发明人 |
HEAVNER GEORGE;KNIGHT DAVID M.;GILES-KOMAR JILL;SCALLON BERNARD;SHEALY DAVID |
分类号 |
C12N15/09;C12N15/74;A01K67/00;A61K31/7088;A61K35/76;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P35/00;A61P37/00;A61P43/00;C07H21/04;C07K16/24;C07K16/42;C12N5/10;C12N15/13;C12N15/79;C12N15/85;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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