发明名称 METHOD OF PREDICTING EFFICIENCY OF RADIOTHERAPY OF MALIGNANT NEOPLASMS OF OROPHARYNGEAL ZONE
摘要 FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to oncology and radiotherapy, and deals with prediction of efficiency of radiotherapy of malignant neoplasms of oropharyngeal zone. Before treatment index of blood microcirculation Iand average degree of oxygenation of mixed blood of microcirculature SOin tumour are registered. Said indices are used to determine perfusion oxygen saturation, and values of blood microcirculation index I' and average degree of oxygenation of mixed blood of microcirculature SO' in intact zone are measured. Average volume blood filling Vin tumour and in intact region V' are registered, level of activity of oxygen metabolism in cells in examined areas MA, MA' is determined by given formulas. If MA/MA'?2.5, efficiency of radiotherapy is predicted, if MA/MA'<2.5, conclusion about high probability of residual volume of tumour after carrying out radiotherapy is made.EFFECT: method makes it possible to predict efficiency of tumour regression to impact of distant radiotherapy still at pre-hospital stage, which in its turn contributes to correct and timely selection of method of treatment in accordance with individual plan.3 ex
申请公布号 RU2500348(C1) 申请公布日期 2013.12.10
申请号 RU20120139064 申请日期 2012.09.12
申请人 GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE ZDRAVOOKHRANENIJA MOSKOVSKOJ OBLASTI "MOSKOVSKIJ OBLASTNOJNAUCHNO-ISSLEDOVATEL'SKIJ KLINICHESKIJ INSTITUT IM. M.F. VLADIMIRSKOGO" 发明人 ROGATKIN DMITRIJ ALEKSEEVICH;POLJAKOV PAVEL JUR'EVICH;BYCHENKOV OLEG ALEKSANDROVICH
分类号 A61B5/1455;A61N5/067 主分类号 A61B5/1455
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