发明名称 |
NYT TRICYKLISK DERIVAT ELLER FARMACEUTISK ACCEPTABLE SALTE DERAF, FREMGANGSMÅDE TIL FREMSTILLING DERAF OG FARMACEUTISK SAMMENSÆTNING INDEHOLDENDE DISSE |
摘要 |
The present invention relates to a novel tricyclic derivative with efficient inhibitory activity against poly(ADP-ribose)polymerases (PARP) or pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition containing the same. The tricyclic derivative of the invention is useful for the prevention or treatment of diseases caused by excess PARP activity, especially neuropathic pain, neurodegenerative diseases, cardiovascular diseases, diabetic nephropathy, inflammatory diseases, osteoporosis, and cancer, by inhibiting the activity of poly(ADP-ribose)polymerases. |
申请公布号 |
DK2364983(T3) |
申请公布日期 |
2013.12.09 |
申请号 |
DK20090826270T |
申请日期 |
2009.11.11 |
申请人 |
JEIL PHARMACEUTICAL CO., LTD. |
发明人 |
MYUNG-HWA, KIM;SEUNG-HYUN, KIM;SAE-KWANG, KU;CHUN-HO, PARK;BO-YOUNG, JOE;KWANG-WOO, CHUN;IN-HAE,YE;JONG-HEE,CHOI;DONG-KYU, RYU;JI-SEON, PARK;HAN-CHANG, LEE;JI-SO, CHOI;YOUNG-CHUL, KIM |
分类号 |
A61K31/4375;A61P25/00;C07D471/04 |
主分类号 |
A61K31/4375 |
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代理人 |
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地址 |
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