MATRIX METALLOPROTEINASE CLEAVABLE PROTEIN POLYMERS FOR CANCER GENE THERAPY
摘要
<p>A delivery system that includes a recombinantly synthesized protein polymer with protease cleavage sites such as matrix metalloproteinase responsive sequences engineered within the protein polymer. The system may be used to treat cancer, wounds, or pathological conditions in other tissues that express excess protease relative to healthy tissue.</p>
申请公布号
WO2013181471(A2)
申请公布日期
2013.12.05
申请号
WO2013US43487
申请日期
2013.05.30
申请人
THE UNIVERSITY OF UTAH RESEARCH FOUNDATION
发明人
GHANDEHARI, HAMIDREZA;CAPPELLO, JOSEPH;FRANDSEN, JORDAN;GUSTAFSON, JOSHUA;GERISH, KHALED;PRICE, ROBERT ANDREW