IMMUNOGENIC COMPOUNDS COMPRISING HIV GP41 PEPTIDE COUPLED TO CRM197 CARRIER PROTEIN

摘要

The present invention relates to the field of vaccines directed against viruses of the HIV family. More particularly, it relates to an immunogenic compound comprising a peptide of the following formula (I) NH 2 -[Nt] y -P-W-N-X -S-X 2 -S-N-X 3 -X 4 -X -X 6 -X 7 -I-W-[Ct] z -COOH (I) which is covalently linked to a carrier protein consisting of a CRM197 protein. It also concerns a composition containing this immunogenic compoundand the uses of theseimmunogenic compounds andcompositionsfor preventing and/or treating a condition caused by the infection of an individual with a HIV virus.