发明名称 |
GLYCOPROTEIN ANTIGEN SIMA135 EXPRESSED IN METASTATIC HUMAN TUMOR CELLS |
摘要 |
PROBLEM TO BE SOLVED: To provide methods to diagnose cancer and to decrease metastasis by cancer cells in a mammal, such as a human, especially to provide the use of a tumor marker protein to create antibodies that can be used to detect increased production of the protein in a cell, and use of the antibodies to decrease metastasis by cancer cells that produce the tumor marker protein.SOLUTION: A monoclonal antibody specifically binds with a soluble form of glycosylated protein comprising a specific amino acid sequence and is used for treating metastatic tumors. |
申请公布号 |
JP2013241416(A) |
申请公布日期 |
2013.12.05 |
申请号 |
JP20130128709 |
申请日期 |
2013.06.19 |
申请人 |
NOVARTIS AG;SCRIPPS RESEARCH INST |
发明人 |
QUIGLEY JAMES P;HOOPER JOHN D;TESTA JACQUELINE E |
分类号 |
C07K16/30;A61K39/395;A61P35/04;C07K14/47;C12N15/09;C12N15/12;C12P21/08;G01N33/574 |
主分类号 |
C07K16/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|