发明名称 GLYCOPROTEIN ANTIGEN SIMA135 EXPRESSED IN METASTATIC HUMAN TUMOR CELLS
摘要 PROBLEM TO BE SOLVED: To provide methods to diagnose cancer and to decrease metastasis by cancer cells in a mammal, such as a human, especially to provide the use of a tumor marker protein to create antibodies that can be used to detect increased production of the protein in a cell, and use of the antibodies to decrease metastasis by cancer cells that produce the tumor marker protein.SOLUTION: A monoclonal antibody specifically binds with a soluble form of glycosylated protein comprising a specific amino acid sequence and is used for treating metastatic tumors.
申请公布号 JP2013241416(A) 申请公布日期 2013.12.05
申请号 JP20130128709 申请日期 2013.06.19
申请人 NOVARTIS AG;SCRIPPS RESEARCH INST 发明人 QUIGLEY JAMES P;HOOPER JOHN D;TESTA JACQUELINE E
分类号 C07K16/30;A61K39/395;A61P35/04;C07K14/47;C12N15/09;C12N15/12;C12P21/08;G01N33/574 主分类号 C07K16/30
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