NOVEL NICKEL COMPLEX, DERIVATIVE OF THE SAME, METHOD OF PRODUCING THE SAME AND APPLICATION TO ANTIOXIDANT

摘要

PROBLEM TO BE SOLVED: To provide a free radical remover which utilizes superoxide dismutase (SOD), one main antioxidant enzyme, and is usable in medicines, health foods, cosmetic compositions and antioxidants for the environment and soil.SOLUTION: There are provided novel five-coordinate di- and trivalent nickel complexes, their derivatives and their six-coordinate derivatives which act as a mimetic compound to the active center of the nickel-containing superoxide dismutase(NiSOD), namely SOD, converting superoxide radicals heterogeneously into hydrogen peroxide and oxygen.