发明名称 NOVEL AND POWERFUL MHC-CLASS II PEPTIDES DERIVED FROM SURVIVIN
摘要 The present invention relates to peptides, nucleic acids, and cells for use in the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
申请公布号 US2013323272(A1) 申请公布日期 2013.12.05
申请号 US201313931413 申请日期 2013.06.28
申请人 IMMATICS BIOTECHNOLOGIES GMBH 发明人 RAMMENSEE HANS GEORG;STEVANOVIC STEFAN;GOUTTEFANGES CECILE;WEINSCHENK TONI;LEWANDROWSKI PETER
分类号 A61K39/00 主分类号 A61K39/00
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