发明名称 |
ANTIBODIES THAT BIND THE GLUTAMATE LIGAND BINDING REGION OF NOTCH3 |
摘要 |
Isolated antibodies that specifically binds to an extracellular conserved ligand binding region of a human Notch receptor and inhibits growth of a tumor are described. Also described are methods of treating cancer, the method comprising administering an anti-Notch antibody in an amount effective to inhibit tumor growth. |
申请公布号 |
US2013323257(A1) |
申请公布日期 |
2013.12.05 |
申请号 |
US201313890805 |
申请日期 |
2013.05.09 |
申请人 |
ONCOMED PHARMACEUTICALS, INC. |
发明人 |
GURNEY AUSTIN L.;SATO AARON KEN;FITCH-BRUHNS MAUREEN |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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