| 摘要 |
This invention relates to a composition comprising climbazole for use in skin lightening. The composition may also comprise lipoicacid and a further ingredient selected from the group consisting of an organic sunscreen, an inorganic sunscreen, an antiperspirant active, a fragrance, a microbicide a chelator, and mixtures thereof. This invention is based on the fact that climbazole has been found to inhibit pigment production i B16 monolayer and MelanoDerm TM cultures. Thus climbazole, when applied topically over an appropriate lenght of time in-vivo, would be expected to cause skin lightening, or to reduce blemishes and/or hyperpigmented spots and/or solar lentigines leading to an improvement in skin tone and evenness. |
