发明名称 |
CERAMIDE LEVELS IN THE TREATMENT AND PREVENTION OF INFECTIONS |
摘要 |
The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. Th e method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients. |
申请公布号 |
WO2013181530(A1) |
申请公布日期 |
2013.12.05 |
申请号 |
WO2013US43608 |
申请日期 |
2013.05.31 |
申请人 |
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI;YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT;UNIVERSITAT DUISBURG-ESSEN |
发明人 |
SCHUCHMAN, EDWARD, H.;GULBINS, ERICH;FUTERMAN, ANTHONY;PEWZNER-JUNG, YAEL |
分类号 |
A61M11/00;A61P31/00 |
主分类号 |
A61M11/00 |
代理机构 |
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