GENOTYPE- OR PHENOTYPE-BASED DRUG FORMULATION

摘要

The invention relates to a combination of two or more pharmaceutically active substances, of which at least one is a metabolic product ("metabolite") of the other ("parent substance"), in particular wherein the dosages thereof are selected in such a way that a genotypically or phenotypically determined variability of the conversion of the parent substance into the metabolite in certain individuals is compensated.