摘要 |
The present invention belongs to the field of pharmaceutical chemicals, and relates to a pegylated artesunate derivative, pharmaceutical composition and use thereof. In particular, the present invention relates to a pegylated artesunate derivative as shown by the general formula (I). The pegylated artesunate derivative of the present invention has activity comparable to that of an artesunate, significantly increased water solubility and stability, and a significantly extended half life in vivo. |
申请人 |
BEIJING KAIZHENG BIOTECH DEVELOPMENT CO. LTD. |
发明人 |
LI, SICHENG;MENG, QINGBIN;MAO, JUNWEN;LI, JINFENG;XU, AN;LIU, JIA;LIANG, YUANJUN;JIA, QIYAN;YAN, JIUFENG;SHEN, XIAOYANG;LIU, HUI;XING, NA |