| 发明名称 |
PROCESS FOR PREPARATION OF LEVONORGESTREL |
| 摘要 |
The present invention provides an improved process for preparation of levonorgestrel (3) which comprises of hydrolysis of 13beta-ethyl-3-methoxy-17alpha-ethynyl-gona-2,5(10)-dien-17beta-ol (2) with an acid in aprotic solvent. The present invention also provides a novel process for purification of crude levonorgestrel (3) by recrystallization from N,N-dimethyl formamide-water; methanol-water mixture. |
| 申请公布号 |
US2013324748(A1) |
申请公布日期 |
2013.12.05 |
| 申请号 |
US201214000056 |
申请日期 |
2012.02.14 |
| 申请人 |
ZADBUKE SWAPNIL AJIT;MEHARE KISHOR GULABRAO;GODBOLE HIMANSHU MADHAV;SINGH GIRIJ PAL;LUPIN LIMITED |
发明人 |
ZADBUKE SWAPNIL AJIT;MEHARE KISHOR GULABRAO;GODBOLE HIMANSHU MADHAV;SINGH GIRIJ PAL |
| 分类号 |
C07J1/00 |
主分类号 |
C07J1/00 |
| 代理机构 |
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