发明名称 INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS
摘要 The present invention relates to compounds of general formula I, wherein the groups R1, R2, R3, m and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
申请公布号 US2013324514(A1) 申请公布日期 2013.12.05
申请号 US201313900121 申请日期 2013.05.22
申请人 HAMPRECHT DIETER;FRATTINI SARA;LINGARD IAIN;PETERS STEFAN;BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 HAMPRECHT DIETER;FRATTINI SARA;LINGARD IAIN;PETERS STEFAN
分类号 A61K31/425;A61K31/192;A61K31/277;A61K31/341;A61K31/382;A61K31/397;A61K31/40;A61K31/416;A61K31/4196;A61K45/06;C07C61/39;C07C235/68;C07C255/54;C07C317/46;C07D205/04;C07D207/48;C07D231/56;C07D249/08;C07D275/02;C07D307/20;C07D335/02 主分类号 A61K31/425
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