| 发明名称 |
SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES |
| 摘要 |
<p>There are provided compounds of the formula (I) wherein X, Y, Z, R1, R2 and R3 are as described herein, enantiomers and pharmaceutically acceptable salts and esters thereof, methods of making those compounds, as well as the use of such compounds as medicaments, especially as anticancer agents.</p> |
| 申请公布号 |
CA2869101(A1) |
申请公布日期 |
2013.12.05 |
| 申请号 |
CA20132869101 |
申请日期 |
2013.05.27 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BARTKOVITZ, DAVID JOSEPH;CHU, XIN-JIE;EHRLICH, GEORGE;LIU, JIN-JUN;MICHEL, HANSPETER;VU, BINH THANH;ZHAO, CHUNLIN |
| 分类号 |
A61K31/40;C07D207/16;C07D401/06;C07D409/04 |
主分类号 |
A61K31/40 |
| 代理机构 |
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