HYBRIDIZATION PROBE ASSAY AND ARRAY

摘要

PROBLEM TO BE SOLVED: To provide a probe specific to human papilloma virus target sequence.SOLUTION: There is provided a probe suitable for coupling with a particulate support such as a microbead, wherein the probe comprises: (a) a coupling group which permits coupling of the probe to a surface of the particulate support; (b) a spacer; and (c) a target-specific oligonucleotide probe sequence, wherein the spacer comprises: (i) an oligonucleotide spacer of at least 15 nucleotides between the target-specific probe sequence and the support coupling group; and optionally (ii) a carbon spacer of 3-50 carbon units between the target-specific probe sequence and the support coupling group.