发明名称 |
Inhibidores de proteínas de la familia HSP90 |
摘要 |
The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I):
(wherein n represents an integer of 0 to 10; R 1 represents substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkoxycarbonyl, CONR 7 R 8 or the like; R 2 represents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group or the like; R 3 and R 5 , which may be the same or different, each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or the like; and R 4 and R 6 , which may be the same or different, each represent a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like) or a prodrug thereof, or a pharmaceutically acceptable salt of said benzoyl compound or said prodrug.
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申请公布号 |
ES2432747(T3) |
申请公布日期 |
2013.12.05 |
申请号 |
ES20040746022T |
申请日期 |
2004.06.10 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
NARA, SHINJI;NAKAGAWA, HIROSHI;KANDA, YUTAKA;NAKASHIMA, TAKAYUKI;SOGA, SHIRO;KAJITA, JIRO;SAITO, JUN-ICHI;SHIOTSU, YUKIMASA;AKINAGA, SHIRO |
分类号 |
C07C49/84;A61K31/12;A61K31/165;A61K31/216;A61K31/40;A61K31/4406;A61K31/4409;A61K31/445;A61K31/451;A61K31/495;A61K31/506;A61K31/5375;A61K31/5377;A61P35/00;A61P43/00;C07C69/738;C07C205/45;C07C235/78;C07D207/12;C07D211/42;C07D211/60;C07D213/40;C07D295/08;C07D295/092;C07D295/12;C07D295/185 |
主分类号 |
C07C49/84 |
代理机构 |
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代理人 |
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地址 |
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