| 发明名称 |
COMPOSITION AND METHOD FOR TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS |
| 摘要 |
PROBLEM TO BE SOLVED: To provide compositions and methods for the diagnosis and treatment of systemic lupus erythematosus (SLE).SOLUTION: The present invention is based on the identification of proteins (including agonist and antagonist antibodies) which are obtained as a result of stimulation of the immune response in mammals, resulting in acquisition of autoimmunity. The resulted PRO polypeptides, agonists and antagonists thereof are also useful to prepare medicines and medicaments for the treatment of SLE. |
| 申请公布号 |
JP2013240329(A) |
申请公布日期 |
2013.12.05 |
| 申请号 |
JP20130121971 |
申请日期 |
2013.06.10 |
| 申请人 |
GENENTECH INC |
发明人 |
ABBAS ALEXANDER;BODARY SARAH;CLARK HILARY;SCHOENFELD JILL;WILLIAMS P MICKEY;WOOD WILLIAM I;WU THOMAS D |
| 分类号 |
C12N15/09;A61K31/675;A61K38/00;A61K39/39;A61K39/395;A61K45/00;A61P7/06;A61P9/00;A61P17/00;A61P17/04;A61P17/06;A61P19/02;A61P21/00;A61P29/00;A61P37/04;A61P37/06;C07K14/435;C07K14/47;C07K16/18;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;C12P21/08;C12Q1/68;G01N33/53 |
主分类号 |
C12N15/09 |
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