发明名称 PROCESS FOR PREPARATION OF DRONEDARONE BY GRIGNARD REACTION
摘要 <p>The invention relates to a novel process for the preparation of dronedarone (I) and pharmaceutically acceptable salts thereof, which comprises reacting of compound of formula (IV) with compound of formula (VI) in a Grignard reaction, and the obtained product is isolated and, if desired, converted into a pharmaceutically acceptable salt thereof. The invention also relates to some novel intermediary compounds and processes for the preparation thereof.</p>
申请公布号 WO2013178337(A1) 申请公布日期 2013.12.05
申请号 WO2013EP01520 申请日期 2013.05.23
申请人 SANOFI 发明人 HUSZAR, CSABA;HEGEDUS, ADRIENN;DOMBRADY, ZSOLT
分类号 C07D307/80 主分类号 C07D307/80
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