发明名称 |
THERAPEUTIC ANTI-TIRC7 ANTIBODIES FOR USE IN IMMUNE RELATED AND OTHER DISEASES |
摘要 |
Provided are specific antibodies against T-cell immune response cDNA7 (TIRC7) costimulatory molecule, which are capable of inhibiting proliferation of peripheral blood mononuclear cells (PBMCs). In particular, high affinity monoclonal and chimeric anti-TIRC7 antibodies are described. Compositions comprising such antibodies and their use for the treatment of immune diseases are provided. |
申请公布号 |
US2013323254(A1) |
申请公布日期 |
2013.12.05 |
申请号 |
US201213725535 |
申请日期 |
2012.12.21 |
申请人 |
UTKU NALAN |
发明人 |
UTKU NALAN |
分类号 |
C07K16/28;C12N15/09;A61K31/7088;A61K35/12;A61K39/00;A61K39/395;A61K45/00;A61K45/06;A61K48/00;A61P29/00;A61P37/02;A61P37/06;C07K7/00;C07K14/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12P21/02;C12P21/08 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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