| 摘要 |
PURPOSE: A lymphatic vascularization composition containing granulocyte-colony stimulating-factors is provided to induce capillarization, cell proliferation, and lymphatic sprout of human lymphatic vascular endothelial cells. CONSTITUTION: A lymphatic vascularization composition contains granulocyte-colony stimulating-factors as an active ingredient. The granulocyte-colony stimulating-factors include granulocyte macrophage colony stimulating factors(GM-CSF) and macrophage colony stimulating factors(MCSF). A composition for preventing or treating lymphedema contains the granulocyte-colony stimulating-factors as an active ingredient. A composition for preventing or treating lymphatic vessel loss or lymphopenia contains the granulocyte-colony stimulating-factors. An agent for enhancing ERK1/2 phosphorylation and Akt phosphorylation contains the granulocyte-colony stimulating-factors as an active ingredient. |
