发明名称 |
BENZOFURO[3,2-C]PYRIDINES AND RELATED ANALOGS AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS FOR THE TREATMENT OF OBESITY, METABOLIC SYNDROME, COGNITION AND SCHIZOPHRENIA |
摘要 |
<p>The present invention relates to benzofuro[3,2-c]pyridine and azepine analogs as serotonin sub-type 6 (5-HT6) modulators, pharmaceutical compositions including these compounds, methods of preparation, and use thereof. These compounds are useful in the treatment of central nervous system disorders including obesity, metabolic syndrome, cognition, schizophrenia, attention deficit hyperactivity disorder, bipolar disorder, rare and orphan diseases, and sleep disorders. The subject compounds have the structure of formula (I) with the substituents being described herein.</p> |
申请公布号 |
EP2668191(A2) |
申请公布日期 |
2013.12.04 |
申请号 |
EP20120736835 |
申请日期 |
2012.01.18 |
申请人 |
ALBANY MOLECULAR RESEARCH, INC. |
发明人 |
GUZZO, PETER, R.;HENDERSON, ALAN, J.;ISHERWOOD, MATTHEW;LEE, CHONG, YEW;GHOSH, ANIMESH;ZHAO, HE, RIVER |
分类号 |
C07D491/04;A61K31/4741;A61P25/00;C07D307/91;C07D491/048;C07D491/08;C07D491/18 |
主分类号 |
C07D491/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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