发明名称 |
AP-9 PEPTIDE FOR USE IN TREATING CARDIAC DAMAGE AFTER ISCHAEMIA/REPERFUSION |
摘要 |
The present invention relates to the use of an EMMPRIN inhibitor for preventing and/or treating cardiac damage arising after an ischemic process followed by reperfusion. The authors of the present invention have observed that EMMPRIN expression increases in subjects who have suffered ischemia/reperfusion, ascertaining that an EMMPRIN inhibitor is capable of reducing the cardiac damage caused after ischemia followed by reperfusion, both in vitro and in vivo . |
申请公布号 |
EP2668960(A2) |
申请公布日期 |
2013.12.04 |
申请号 |
EP20110845312 |
申请日期 |
2011.12.01 |
申请人 |
FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (CINC) |
发明人 |
ZARAGOZA SÁNCHEZ, CARLOS;GÓMEZ PARRIZAS, MÓNICA;LAVÍN PLAZA, BEGOÑA;TARÍN CEREZO, CARLOS |
分类号 |
A61K39/395;A61K38/00;A61K39/00;A61K47/00;A61P9/10;B82Y5/00;C07K14/705;C07K16/28;G01N33/543 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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