发明名称 |
METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY |
摘要 |
Provided herein are methods and compositions related to a retinoid receptor-selective pathway. As described herein, this pathway can be targeted to manipulate a tumor microenvironment. For example, the methods and compositions described herein can be used to induce apoptosis in a cancer cell. Further, the compositions described herein, including Sulindac and analogs thereof, can be used to target this pathway for the treatment or prevention of cancer in human patients. |
申请公布号 |
EP2571497(A4) |
申请公布日期 |
2013.12.04 |
申请号 |
EP20110778467 |
申请日期 |
2011.05.06 |
申请人 |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE;XIAMEN UNIVERSITY |
发明人 |
ZHANG, XIAO-KUN;SU, YING;ZHOU, HU;LIU, WEN;HUANG, PEI-QIANG |
分类号 |
A61K31/015 |
主分类号 |
A61K31/015 |
代理机构 |
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