发明名称 CARRIERS FOR THE LOCAL RELEASE OF HYDROPHILIC PRODRUGS
摘要 Disclosed is a carrier for the local, targeted administration of a hydrophobic drug. The hydrophobic drug is rendered in to a hydrophilic prodrug thereof, and is contained in the lumen of a thermosensitive liposome or polymersome. Upon administration of the carrier, heat can be applied at the locus where the drug is to be released. After release of the prodrug, it will be activated so as to turn into the active drug.
申请公布号 EP2667848(A1) 申请公布日期 2013.12.04
申请号 EP20120703350 申请日期 2012.01.25
申请人 KONINKLIJKE PHILIPS N.V. 发明人 GRUELL, HOLGER;LANGEREIS, SANDER;SIO, CHARLES FREDERIK
分类号 A61K9/00;A61K9/127 主分类号 A61K9/00
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