Delivery system for an active substance

摘要

A delivery system for an active substance, comprises a substrate 2 on which the substance is loaded for subsequent release, wherein: (i) the substrate has been at least partially coated with a polymer 3 using plasma deposition (preferably pulsed plasma deposition); (ii) the active substance is present as a guest molecule within a cyclodextrin inclusion complex 1; and (iii) the inclusion complex is bound to the polymer through a chemical linkage to formed between a hydroxyl group on the cyclodextrin and a functionalgroup on the polymer. The system may be used to control the release of an active substance such as a perfume from a substrate such as a textile. Also provided are methods for preparing (a) the delivery system and (b) a functionalised substrate for use as part of the system, in which the polymer is suitably reacted with a cyclodextrin using an SN2 nucleophilic substitution reaction, in particular a Williamson ether synthesis reaction.