发明名称 |
Process for preparing 5-fluoro-1H-pyrazolo [3,4-B] pyridin-3-amine and derivatives therof |
摘要 |
The present invention relates to a process for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine in high yield and purity. The present invention also relates to processes for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine derivatives. These processes are useful for preparing biologically active compounds, particularly certain GSK-3 inhibitors, or derivatives thereof. |
申请公布号 |
US8598361(B2) |
申请公布日期 |
2013.12.03 |
申请号 |
US201213347926 |
申请日期 |
2012.01.11 |
申请人 |
JIMENEZ JUAN-MIGUEL;MILLER ANDREW;COLLIER PHILIP;GREEN JEREMY;DROS ALBERT;GAO HUAI;HAMON SYLVAIN;VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
JIMENEZ JUAN-MIGUEL;MILLER ANDREW;COLLIER PHILIP;GREEN JEREMY;DROS ALBERT;GAO HUAI;HAMON SYLVAIN |
分类号 |
C07D215/04 |
主分类号 |
C07D215/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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