MÉTODO PARA PREPARAR UM POLIPEPTÍDEO, POLIPEPTÍDEO, E, MÉTODO PARA REALIZAR UMA REAÇÃO CATALISADA POR LIPASE

摘要

Molecular dynamics (MD) simulation on the three-dimensional structure of Candida anrtarctica lipase B revealed two hitherto unknown lids with a marked mobility, and this discovery was used to design lipolytic enzyme variants with increased lipolytic enzyme activity, like variants in which residue 147 has been altered.