发明名称 METHOD FOR CONTROLLING BINDING OF CELLS TO A SUBSTRATE
摘要 The invention relates to a method for promoting the adhesion of cells to a substrate to which these cells usually have no or only low affinity, wherein the adhesion of the cells to the substrate is promoted by supplying the cells with the non-muscle myosin II inhibitor Blebbistatin so as to enable the cells to attach to surfaces to which they otherwise would not have sufficient affinity. Surprisingly, supplying the cells with the inhibitor enhances the capability of these cells to attach to surfaces to which they usually have no or only low affinity, for example, PTFE (Teflon®). The invention further concerns uses of the non-muscle myosin II inhibitor Blebbistatin and devices having at least one surface which is coated with cells that have no or only low affinity to said surface.
申请公布号 KR20130131363(A) 申请公布日期 2013.12.03
申请号 KR20137014780 申请日期 2011.11.09
申请人 LONZA COLOGNE GMBH 发明人 SCHENK JUDITH;VAN DEN BOS CHRISTIAN;ROSENBAUM CLAUDIA;NIE YING
分类号 C12N5/0775;A61L27/38 主分类号 C12N5/0775
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