发明名称 |
METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF BREAST CANCER METASTASIS. |
摘要 |
<p>The present invention relates to a method for the diagnosis or prognosis of breast cancer metastasis that comprises determining whether the MAF gene is amplified in a primary-tumour sample. Furthermore, the invention also relates to a method for the diagnosis or prognosis of ER breast cancer mestastasis and also a method for determining the propensity for developing metastasis to bone as opposed to metastasis to other organs, comprising determining the expression level of the c-MAF gene. Lastly, the invention relates to the use of a c-MAF inhibitor as therapeutic target for the treatment of ER breast cancer metastasis.</p> |
申请公布号 |
MX2013003880(A) |
申请公布日期 |
2013.12.02 |
申请号 |
MX20130003880 |
申请日期 |
2011.10.05 |
申请人 |
INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS |
发明人 |
ROGER GOMIS CABRE;MARIA TARRAGONA SUNYER;ANNA ARNAL ESTAPE;MILICA PAVLOVIC |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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