发明名称 Pyrazolo [4,3-D] pyrimidines useful as kinase inhibitors
摘要 The present invention relates to novel compounds of formula (I) that are capable of inhibiting one or more kinases, especially SYK (Spleen Tyrosine Kinase), LRRK2 (Leucine-rich repeat kinase 2) and/or MYLK (Myosin light chain kinase) or mutants thereof. The compounds find applications in the treatment of a variety of diseases. These diseases include autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, alzheimer's disease, parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases.
申请公布号 AP201307253(D0) 申请公布日期 2013.11.30
申请号 AP20130007253 申请日期 2012.04.23
申请人 ORIGENIS GMBH 发明人 TRAUBE NADINE;ALMSTETTER MICHAEL;TREML ANDREAS
分类号 C07D487/04;A61K31/519 主分类号 C07D487/04
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