发明名称 |
Chiral synthesis of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[2,3-dihydroxy-propyl] |
摘要 |
<p>The present invention relates to a novel enantioselective method of preparing (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-5 methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide.</p> |
申请公布号 |
AP201307257(D0) |
申请公布日期 |
2013.11.30 |
申请号 |
AP20130007257 |
申请日期 |
2012.05.24 |
申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
MAYER AGATHE CHRISTINE;FEY PETER |
分类号 |
C07C303/38;C07C303/40;C07C309/82;C07C311/28 |
主分类号 |
C07C303/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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