NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF

摘要

127[Abstract]NOVEL, CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF D The present invention relates to novel cephaicaporinderivatives represented by Chemical Formula 1.W°)1144,„' ;.R2(1)Wherein, X, Y, L, RI, and R2 are as same as defined in the description of the invention. 10 The bresent invent: on also reiates to pharmaceuticalantibiotic compositions comprising a novel celphalosporin derivative represented by Chemical Formula I, a prbdrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, or a oharracentically acceptable salt thereof as an effective15 ingredient.Abcording to the present invention, novel cephalosporin derivatives, a prodrug thereof, a hydrate thereof, a solvate therebf, an isomer thereof, or a pharmaceutically acceptable salt thereof as an effertive inoredient for the broad spectrum. of antibiotic resistant, low tozicity, particularly in. Gram-negative bacteria, which can be useful with strong antimicrobial activity.Figure 1