PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF INFLUENZA VIRUS INFECTION COMPRISING SULFATED EXOPOLYSACCHARIDE AS AN ACTIVE INGREDIENT

摘要

PURPOSE: A pharmaceutical composition or a health food composition containing sulfur-containing extracellular polysaccharides p-KG03 is provided to prevent and treat influenza viral infection. CONSTITUTION: A pharmaceutical composition for preventing or treating influenza virus A infection contains sulfur-containing extracelullar p-KG03 as an active ingredient, isolated from Gyrodinium impudicum KG03(KCTC 10325BP). The optimal temperature and pH of extracellular polysaccharide p-KG03 is 25-30 deg.C. and pH 8-9. The composition contains an anti-influenza virus formulation such as zanmivir, oseltamivir, amandadine, rimantadine, or ribavirin. A health food composition for preventing or treating influenza viral infection contains sulfur-containing extracelullar p-KG03 as an active ingredient. [Reference numerals] (AA) PFU(control group %); (BB) Concentration(ug/ml)