发明名称 PHARMACEUTICAL MOUTHWASH-TYPE PREPARATIONS BASED ON CHLORHEXIDINE METAL COMPLEXES AND PROCESS FOR PREPARING THE SAME
摘要 <p>The invention relates to a pharmaceutical preparation of the mouthwash type and to a process for preparing the same. According to the invention, the preparation comprises 0.03...0.1% metal complexes of cyclohexidine with auxiliary substances consisting of polyoxyethylene-20 sorbitan monooleate, polyoxyl-40 hydrogenated castor oil, glycerol, ethyl alcohol, mint oil and water, presented as clear violet-coloured solutions having a slightly acid pH and a relative density higher than water. The process claimed by the invention consists in weighing the starting materials, mixing the same, triturating, hot dissolving and mass completion followed by the control and conditioning of the final product.</p>
申请公布号 RO127722(B1) 申请公布日期 2013.11.29
申请号 RO20100001222 申请日期 2010.11.29
申请人 UNIVERSITATEA "OVIDIUS" DIN CONSTANTA;UNIVERSITATEA POLITEHNICA DIN BUCURESTI;UNIVERSITATEA DIN BUCURESTI;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU STIINTE BIOLOGICE;PRODIAGNOSTIC S.R.L. 发明人 NEGREANU-PIRJOL TICUTA;NEGREANU-PIRJOL BOGDAN-STEFAN;GURAN CORNELIA;CALINESCU MIRELA;OANCEA ANCA;GORUN ELENA;RONCEA FLORENTINA-NICOLETA;DUMITRU FLORINA;MEGHEA AURELIA;BADEA NICOLETA;TARALUNGA GHEORGHE;AMARIEI CORNELIU;MOLDOVAN LUCIA
分类号 A61K9/08;A61K33/38;C07C279/26 主分类号 A61K9/08
代理机构 代理人
主权项
地址