发明名称 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS
摘要 This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective, amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I).
申请公布号 EA018880(B1) 申请公布日期 2013.11.29
申请号 EA20110070061 申请日期 2009.06.19
申请人 H. LUNDBECK A/S 发明人 RITZEN ANDREAS;KEHLER JAN;LANGGAARD MORTEN;NIELSEN JACOB;KILBURN JOHN, PAUL;FARAH MOHAMED, M.
分类号 C07D403/12;A61K31/4184;A61K31/4353;A61K31/519;A61P25/00;C07D487/04 主分类号 C07D403/12
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